：http://hatano.yz.yamagata-u.ac.jp/NONNNNOOOR1R21,2-diamineR3R3R2R1R1OR21,2-diolR1RCF3NONNNNinclusioncomplexofbisphenolADRD156TMINOinclusioncomplexofoctylphenolButaverineMC-PROXYLo-vinyl-fluoroacetophenone31Super-resolution fluorescence microscopyDevelopment of new fluorescent proteinsApplication of diatomsSuper-resolution fluorescence microscopy systemScolionema suvaenseCoscinodiscuswailesiiFluorescence imageSuper-resolution imageFluorescent protein ScSuFPOptical patterning ondiatom flustulesExpression of fluorescentprotein in diatomIllustrationChemistrybased on host-guest inclusion chemistrylabels homo-allylamine We already had several projects with reliable companies! Yamagata UniversityGraduate School of Science and Engineering We also would like to joint exciting research for your Research Interest：Organic Synthesis, Organometallics, Inclusion company!OHOHOR2HOOCNOHOOHHOCOOHCOOMeCH2NR1R2Yamagata University Graduate School of Science and Engineering Research InterestE-mail ：hatano@yz.yamagata-u.ac.jpOrganic Synthesis, Organometallics, Inclusion ChemistryTel ：+81-238-26-3117E-mail ・ hatano@yz.yamagata-u.ac.jpFax：+81-238-26-3413Tel ・ +81-238-26-3117Fax ・ +81-238-26-3413HP HP・https://bio.yz.yamagata-u.ac.jp/L-hatano.htmlContent：Content1.Resolution of biological actives and chiral compounds based on 1.Resolution of biological actives and chiral compounds 2.Development of C-C bond formation using chiral molecular 2.Development of C-C bond formation using chiral molecular 3.Synthesis and properties of spin trapping reagents and labels 3.Synthesis and properties of spin trapping reagents and Ourresearchgrouppursuesusefulnewreactivityandgeneralmethodsforpowerfulandreliablechemicaltransformation,andeffective Our research group pursues useful new reactivity and resolutionsofbiologicalactivecompoundsandchiralligandsusinggeneral methods for powerful and reliable chemical inclusionchemistry.Ourcurrentfocusesareoncarbon-carbonbondtransformation, and effective resolutions of biological active formationusingchiralmolecularcatalyst,synthesisofspinlabelcompounds and chiral ligands using inclusion chemistry. Our reagentsbasedonisoindolestructure,andresolutionofchiralligandscurrent focuses are on carbon-carbon bond formation using usinghost-guestinclusionchemistry.chiral molecular catalyst, synthesis of spin label reagents based on isoindole structure, and resolution of chiral ligands Appealingpoint:using host-guest inclusion chemistry.Wealreadyhadseveralprojectswithreliablecompanies!Wealsowouldliketojointexcitingresearchforyourcompany!Special objectiveshost-guest inclusion chemistrycatalystcatalystContent：ContentWe aim to develop new super-resolution microscope system with We aim to develop new super-resolution microscope nanometer resolution and single molecule level sensitivity. system with nanometer resolution and single molecule level Fluorescent proteins are widely used in bio-imaging to observe sensitivity. living organisms. By developing a new photoswitchingfluorescent Fluorescent proteins are widely used in bio-imaging to protein, we aim to realize a super-resolution fluorescent microscope observe living organisms. By developing a new photoswitching with higher spatial resolution.fluorescent protein, we aim to realize a super-resolution Diatoms are primary producers responsible for about half of carbon fluorescent microscope with higher spatial resolution.dioxide fixation in the ocean and are important photosynthetic Diatoms are primary producers responsible for about half organisms that support the marine ecosystem. We would like to of carbon dioxide fixation in the ocean and are important photosynthetic organisms that support the marine clarify the mechanism of formation of the silica flustulesof diatoms ecosystem. We would like to clarify the mechanism of using gene manipulation technology and super-resolution formation of the silica flustules of diatoms using gene fluorescence microscopy. We hope to contribute to the SDGs of manipulation technology and super-resolution fluorescence energy and food problems in the future.microscopy. We hope to contribute to the SDGs of energy and food problems in the future.Appealing point：Development of new optical measurement systems. Gene manipulation of micro organisms. Development of fluorescent Special objectivesproteins with unusual photophysicalproperties. Development of new optical measurement systems. Gene manipulation of micro organisms. Development of fluorescent proteins with unusual photophysical properties.Yamagata UniversityGraduate School of Science and Engineering Research Interest ：Optical nanoscopyYamagata University Graduate School of Science and Engineering E-mail ：hotta@yz.yamagata-u.ac.jpResearch InterestOptical nanoscopyTel ：+81-238-26-3032Fax：+81-238-26-3032E-mail ・ hotta@yz.yamagata-u.ac.jpTel ・ +81-238-26-3032HP ：http://acebe.yz.yamagata-u.ac.jp/laboratory/Fax ・ +81-238-26-3032HP・http://acebe.yz.yamagata-u.ac.jp/laboratory/biochemistry/ base/labo_032/biochemistry/base/labo_032/Associate Professor Jun-ichi HottaAssociate Professor Jun-ichi HottaDevelopment of Novel Organic Reaction and Resolution of Chiral CompoundsDevelopment of Novel Organic Reaction and Resolution of Chiral CompoundsAssociate ProfessorBunpei HATANO (Ph. D.)Associate Professor Bunpei Hatano (Ph. D.)Bio-imaging with super-resolution fluorescence microscopyBio-imaging with super-resolution fluorescence microscopyCurrent focuses
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