37NNaannoo--ssccaallee ssuurrffaaccee rroouugghhnneessssSSuurrffaaccee ttooppooggrraapphhyyBBiiooffuunnccttiioonnaalliizzeeddNNPPss ffoorr nnaannoommeeddiicciinneeUUVV--oozzoonnee ttrreeaattmmeenntt・・Biocompatibility・・Cytotoxicity・・Differentiation・・Proliferation・・Gene expressionBuilding Blocks : Biologically active and Functional ExchangeCatalytic ReactionAtom economyGreen chemistryContentContent：Our research aim is development of biofunctionalmaterials for Our research aim is development of biofunctional materials cellular function. Microenvironment, for instance surface topography for cellular function. Microenvironment, for instance surface or/and surface chemical composition, act as physicochemical stimuli topography or/and surface chemical composition, act as which effect to gene expression and cell adhesion. Therefore, physicochemical stimuli which effect to gene expression and biofunctionalmaterials could lead to increase biocompatibility.cell adhesion. Therefore, biofunctional materials could lead We use various types of cells such as osteoblasts, endothelial cells, to increase biocompatibility.mesenchymal stem cells, and keratinocyte, and etcfor cell-based analysis of the materials.Also, cytotoxicity of drug candidates, We use various types of cells such as osteoblasts, chemicals, and environmental substances are also able to analyze endothelial cells, mesenchymal stem cells, and keratinocyte, using these types of cells. and etc for cell-based analysis of the materials. Also, cytotoxicity of drug candidates, chemicals, and Appealing point：environmental substances are also able to analyze using We positively promote R&D based on industry-academia these types of cells. collaboration.Special objectives We positively promote R&D based on industry-academia collaboration.Yamagata UniversityGraduate School of Science and Engineering Research Interest ：BioengieeringContentContent：Our research:Our research: Novel catalytic reaction systems for preparation of Novel catalytic reaction systems for preparation of functional functional chemicals from biomass, low toxicity, inexpensive chemicals from biomass, low toxicity, inexpensive or halogen-free or halogen-free materials as starting materials. materials as starting materials. Yamagata University Graduate School of Science and Engineering E-mail：: migita@yz.yamagata-u.ac.jpResearch InterestTel ：+81-238-26-3740BioengieeringIllustrationSSuurrffaaccee ttrreeaattmmeenntt OsteoblastEndothelial cellKeratinocyteIllustrationRaw materialBiomass,Low toxicity, orHalogen freeOrganic synthesis for a sustainable society Development of noble catalytic reaction systemChallenge to the synthesis of new functional chemicalsCCeellll--bbaasseedd aannaallyyssiissHP ：https://sites.google.com/view/miglabE-mail ・ migita@yz.yamagata-u.ac.jpTel ・ +81-238-26-3740HP・https://sites.google.com/view/miglabProductmaterialsCatalytic reaction should be atom economy and green chemistry. Catalytic reaction should be atom economy and green We believe that the development of novel reaction systems lead to chemistry.realize organic chemical synthesis aimed at a sustainable society. We believe that the development of novel reaction systems lead to realize organic chemical synthesis aimed at a sustainable society. Appealing point:We challenge for the construction of a new organic synthesis that is Special objectivesfriendly to both the environment and human using a novel catalytic reaction systems. We challenge for the construction of a new organic synthesis that is friendly to both the environment and human using a novel catalytic reaction systems.Yamagata UniversityGraduate School of Science and Engineering Research Interest：Organic chemistry, Catalytic Reaction Yamagata University Graduate School of Science and Engineering Research InterestOrganic chemistry, Catalytic Reaction E-mail ：minakawa@yz.yamagata-u.ac.jpTel ：+81-238-26-3470E-mail ・ minakawa@yz.yamagata-u.ac.jpTel ・ +81-238-26-3470Fax：+81-238-26-3470Fax ・ +81-238-26-3470Biofunctional Materials and Cell-based analysisBiofunctionalMaterials and Cell-based analysisNovel Catalytic Reaction SystemNovel Catalytic Reaction SystemAssistant ProfessorSatoshi MigitaAssistant Professor Satoshi MigitaAssistant Professor Maki MinakawaAssistant Professor MINAMAWA, Maki
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