Hollow Microcapsule from Microbubble TemplateDevelopment of Microbubble Generation Technology and its Application 65IllustrationSmall-diameter blood vessel modelElectro-tensile bioreactor for the culture of regenerative cardiac tissue in a conventional CO2incubatorIllustrationMicrobubble Generation Device using UltrasoundMicrobubbleMicrobubbleEncapsulationEncapsulation5μm5μm5μmRegenerative cardiac ringApplication ExampleContent：Efficient differentiation from stem cells into high-quality functional Efficient differentiation from stem cells into high-quality cells is essential for regenerative medicine. It is known that the functional cells is essential for regenerative medicine. It is known that the biochemical and biophysical factors are biochemical and biophysical factors are critical to the differentiation. critical to the differentiation. One major project at the lab is One major project at the lab is to differentiate human iPScells to differentiate human iPS cells (hiPSC) into heart cells. We (hiPSC) into heart cells. We take advantages of the cardiac take advantages of the cardiac extracellular matrix (cECM) extracellular matrix (cECM) to make cell culture substrate eyeing on to make cell culture substrate eyeing on the beneficial the beneficial biochemical composition in cECMfor the cardiac biochemical composition in cECM for the cardiac differentiation. Furthermore, we create favorable biophysical differentiation. Furthermore, we create favorable biophysical environment for the cardiac differentiation by developing a novel environment for the cardiac differentiation by developing a novel electro-tensile bioreactor. In addition, we are electro-tensile bioreactor. In addition, we are attempting to create anattempting to create an architecture in which flexible architecture in which flexible conductive tracts between atrial and conductive tracts between atrial and ventricular cells can ventricular cells can propagate, producing a new heart model.propagate, producing a new heart model.Appealing point：Collaboration is key to my research. I have been collaborating with professors and experts in medical science and biomechanics. I could contribute my skill and knowledge in experimental and theoretical Collaboration is key to my research. I have been research and in device and novel biomaterial development. I am also collaborating with professors and experts in medical science and biomechanics. I could contribute my skill and knowledge looking forward to industry-academia collaboration. in experimental and theoretical research and in device and novel biomaterial development. I am also looking forward to Yamagata UniversityGraduate School of Science and Engineering industry-academia collaboration. Research Interests：biomaterial developmentYamagata University Graduate School of Science and Engineering Research InterestContentSpecial objectivesContentContent：[Microbubble Generation Technology][Microbubble Generation Technology]Bubbles with diameters less than 100μm (Microbubbles) are Bubbles with diameters less than 100μm (Microbubbles) gaining significant attention owing to their properties; large surface are gaining significant attention owing to their properties; area per unit volume, low buoyancy, self-pressurization and large surface area per unit volume, low buoyancy, self-acoustical property. Our laboratory is developing novel microbubble pressurization and acoustical property. Our laboratory is generators using ultrasound. In addition, we are developing developing novel microbubble generators using ultrasound. In addition, we are developing applications of microbubbles applications of microbubbles for disinfection, cleaning, and for disinfection, cleaning, and fabrication process of novel fabrication process of novel materials.materials.[Hollow Microcapsule from Microbubble Template][Hollow Microcapsule from Microbubble Template]We develop a fabrication method for hollow microcapsules from We develop a fabrication method for hollow microcapsules microbubble templates. The method is based on direct encapsulation from microbubble templates. The method is based on direct of microbubbles, and thus does not require a liquid-or solid-core encapsulation of microbubbles, and thus does not require a decomposition process. These microbubbles can be used as thermal liquid- or solid-core decomposition process. These and acoustic insulators as well as microbubble contrast agents.microbubbles can be used as thermal and acoustic insulators as well as microbubble contrast agents.Appealing point：Our microbubble generation device using ultrasound is available for Special objectiveshigh-temperature and high-viscosity liquid in addition to water. Our microbubble generation device using ultrasound is available for high-temperature and high-viscosity liquid in addition to water.Yamagata UniversityGraduate School of Science and Engineering Research Interest ：Bubble DynamicsYamagata University Graduate School of Science and Engineering E-mail ：makuta@yz.yamagata-u.ac.jpResearch InterestTel ：+81-238-26-3258Bubble DynamicsFax：+81-238-26-3258E-mail ・ makuta@yz.yamagata-u.ac.jpTel ・ +81-238-26-3258Fax ・ +81-238-26-3258HP ：http://mb-lab.yz.yamagata-u.ac.jp/HP・http://mb-lab.yz.yamagata-u.ac.jp/3D regenerative tissuestem cell engineeringbiomaterial developmentE-mail ：zhgfeng@yz.yamagata-u.ac.jp3D regenerative tissuestem cell engineeringTel ：+81-238-26-3728E-mail ・ zhgfeng@yz.yamagata-u.ac.jpFax：+81-238-26-3728Tel ・ +81-238-26-3728HP ：http://mech.yz.yamagata-u.ac.jp/lab/robo/feng_lab.htmlFax ・ +81-238-26-3728HP・http://mech.yz.yamagata-u.ac.jp/lab/robo/feng_lab.htmlStem Cell Differentiation and Regenerative Tissue Construction with Natural BiomaterialsAssociate Professor Zhonggang FengAssociate Professor ZhonggangFeng Stem Cell Differentiation and Regenerative Tissue Construction with Natural Biomaterials Development of Microbubble Generation Technology and its Application Associate Professor ToshinoriMakutaAssociate Professor Toshinori Makuta
元のページ ../index.html#67