82informationBiosensor, Analytical ChemistrysuchasmassPlease put your photograph. Content：ContentAquartzcrystaloscillatorwithhighfrequencystabilityisadevice A quartz crystal oscillator with high frequency stability is a thatanddevice that provides mechanical information such as mass viscoelasticityaboutmaterialsontheoscillator.Thisdevicecanbeand viscoelasticity about materials on the oscillator. This usedinamicrobalanceowingtoitsabilitytomeasuremasschangesdevice can be used in a microbalance owing to its ability to measure mass changes at a nano-gram level. atanano-gramlevel. We developed a quartz crystal oscillator-based biosensor Wedevelopedaquartzcrystaloscillator-basedbiosensorandand demonstrated its application to in situ observation of demonstrateditsapplicationtoinsituobservationofbiomolecularbiomolecular interactions and enzymatic reactions. In interactionsandenzymaticreactions.Inaddition,weobservedaddition, we observed structural changes in proteins and structuralchangesinproteinsandevaluateddynamicviscoelasticityevaluated dynamic viscoelasticity of polymers by ofpolymersbymeasurementoftheoscillationenergydissipation.measurement of the oscillation energy dissipation.Appealingpoint：Special objectivesThistechniqueisexpectedtobeappliedtotheevaluationof This technique is expected to be applied to the evaluation biomolecularactivitiesandpropertiesofpolymersatamolecularof biomolecular activities and properties of polymers at a level.Weaddressthedevelopmentofthenoveldevicethatanyonemolecular level. We address the development of the novel canuseanywhere.device that anyone can use anywhere.Yamagata UniversityGraduate School of Science and Engineering Research Interest ：Biomolecular Engineering,Yamagata University Graduate School of Science and Engineering Research InterestE-mail ：hfurusaw@yz.yamagata-u.ac.jpBiomolecular Engineering, Biosensor, Analytical ChemistryTel ：+81-238-26-3841E-mail ・ hfurusaw@yz.yamagata-u.ac.jpFax：+81-238-26-3841Tel ・ +81-238-26-3841Fax ・ +81-238-26-3841HP ：http://furusawa-lab.yz.yamagata-u.ac.jp/wp/HP・http://furusawa-lab.yz.yamagata-u.ac.jp/wp/providesmechanicalIn situ Observation of Biomolecular BehaviorsProfessor Hiroyuki FurusawaIn situObservation of Biomolecular BehaviorsProfessor Hiroyuki Furusawa
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